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Yixin Zhang, Lu Zhou, Liqing Chen, Yang Guo, Fanhui Guo, Jianjun Wu, Baiqian Dai
《化学科学与工程前沿(英文)》 2021年 第15卷 第3期 页码 518-527 doi: 10.1007/s11705-020-1926-9
Probes and nano-delivery systems targeting NAD(P)H:quinone oxidoreductase 1: a mini-review
《化学科学与工程前沿(英文)》 2023年 第17卷 第2期 页码 123-138 doi: 10.1007/s11705-022-2194-7
关键词: NAD(P)H:quinone oxidoreductase 1 cancer therapy target probe nanosystem
《医学前沿(英文)》 页码 924-938 doi: 10.1007/s11684-023-1004-z
关键词: ovarian cancer lncRNA LOC646029 metastasis microRNA 627-3p SPRED1
PAK1 is a novel cardiac protective signaling molecule
null
《医学前沿(英文)》 2014年 第8卷 第4期 页码 399-403 doi: 10.1007/s11684-014-0380-9
We review here the novel cardiac protective effects of the multifunctional enzyme, p21-activated kinase 1 (PAK1), a member of a serine/threonine protein kinase family. Despite the large body of evidence from studies in noncardiac tissue indicating that PAK1 activity is key in the regulation of a number of cellular functions, the role of PAK1 in the heart has only been revealed over the past few years. In this review, we assemble an overview of the recent findings on PAK1 signaling in the heart, particularly its cardiac protective effects. We present a model for PAK1 signaling that provides a mechanism for specifically affecting cardiac cellular processes in which regulation of protein phosphorylation states by protein phosphatase 2A (PP2A) predominates. We discuss the anti-adrenergic and antihypertrophic cardiac protective effects of PAK1, as well as its role in maintaining ventricular Ca2+ homeostasis and electrophysiological stability under physiological, β-adrenergic and hypertrophic stress conditions.
Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence
Huanping Wang, Haitao Meng, Jinghan Wang, Yinjun Lou, Yile Zhou, Peipei Lin, Fenglin Li, Lin Liu, Huan Xu, Min Yang, Jie Jin
《医学前沿(英文)》 2020年 第14卷 第3期 页码 327-334 doi: 10.1007/s11684-019-0712-x
关键词: 1p32.3 deletion 1q21 gain prognosis multiple myeloma FISH bortezomib thalidomide
用高光谱发光法研究Cu(Inx,Ga1–x)Se2 (CIGS)模块中由P1引起的功率损耗的成因 Article
César Omar Ramírez Quiroz, Laura-Isabelle Dion-Bertrand, Christoph J. Brabec, Joachim Müller, Kay Orgassa
《工程(英文)》 2020年 第6卷 第12期 页码 1395-1402 doi: 10.1016/j.eng.2019.12.019
关键词: Cu(Inx Ga1–x)Se2 电池到模块的效率差距 由P1引起的功率损耗 高光谱光致发光 激光烧蚀短程热效应
Adsorption of 1,3-propanediol from synthetic mixture using polymeric resin as adsorbents
TANTAYAKOM, P. PRASITCHOKE, C. MUANGNAPOH
《化学科学与工程前沿(英文)》 2009年 第3卷 第1期 页码 52-57 doi: 10.1007/s11705-009-0087-7
关键词: adsorption 1 3-propanediol glycerol polymeric resin adsorption isotherm
大规模高效网络计算中的网络技术发展趋势 Review
苏金树1,2,赵宝康1,戴艺1,曹继军1,魏子令1,赵娜1,宋丛溪1,刘宇靖1,夏雨生2
《信息与电子工程前沿(英文)》 2022年 第23卷 第12期 页码 1733-1746 doi: 10.1631/FITEE.2200217
关键词: 超级计算;云计算;网络技术;发展趋势
基于孔径耦合微带结构馈电的单脉冲透射阵天线 Correspondence
寇娜1,2,3,余世星1,2,3,丁召1,2,3,张正平1,2,3
《信息与电子工程前沿(英文)》 2022年 第23卷 第3期 页码 502-510 doi: 10.1631/FITEE.2000547
关键词: 孔径耦合;单脉冲天线;微带;透射阵列
Inhibition of the nuclear export of p65 and IQCG in leukemogenesis by NUP98-IQCG
null
《医学前沿(英文)》 2016年 第10卷 第4期 页码 410-419 doi: 10.1007/s11684-016-0489-0
NUP98 fuses with approximately 34 different partner genes via translocation in hematological malignancies. Transgenic or retrovirus-mediated bone marrow transplanted mouse models reveal the leukemogenesis of some NUP98-related fusion genes. We previously reported the fusion protein NUP98-IQ motif containing G (IQCG) in a myeloid/T lymphoid bi-phenoleukemia patient with t(3;11) and confirmed its leukemogenic ability. Herein, we demonstrated the association of NUP98-IQCG with CRM1, and found that NUP98-IQCG expression inhibits the CRM1-mediated nuclear export of p65 and enhances the transcriptional activity of nuclear factor-κB. Moreover, IQCG could be entrapped in the nucleus by NUP98-IQCG, and the fusion protein interacts with calmodulin via the IQ motif in a calcium-independent manner. Therefore, the inhibition of nuclear exports of p65 and IQCG might contribute to the leukemogenesis of NUP98-IQCG.
《医学前沿(英文)》 doi: 10.1007/s11684-023-1016-8
关键词: p53 mutation triple-negative breast cancer decitabine DNMT1 IRF7 innate immune response
Qiong CAI, Nigel P. BRANDON, Claire S. ADJIMAN,
《能源前沿(英文)》 2010年 第4卷 第2期 页码 211-222 doi: 10.1007/s11708-010-0037-6
关键词: hydrogen production renewable energy solid oxide electrolyser cell 1D dynamic model dynamic behaviour temperature control
null
《医学前沿(英文)》 2016年 第10卷 第3期 页码 286-296 doi: 10.1007/s11684-016-0456-9
Exogenic electric fields can effectively accelerate bone healing and remodeling through the enhanced migration of bone marrow mesenchymal stem cells (BMSCs) toward the injured area. This study aimed to determine the following: (1) the direction of rat BMSC (rBMSC) migration upon exposure to a direct current electric field (DCEF), (2) the optimal DCEF intensity and duration, and (3) the possible regulatory role of SDF-1/CXCR4 axis in rBMSC migration as induced by DCEF. Results showed that rBMSCs migrated to the positive electrode of the DCEF, and that the DCEF of 200 mV/mm for 4 h was found to be optimal in enhancing rBMSC migration. This DCEF strength and duration also upregulated the expression of osteoblastic genes, including ALP and OCN, and upregulated the expression of ALP and Runx2 proteins. Moreover, when CXCR4 was inhibited, rBMSC migration due to DCEF was partially blocked. These findings indicated that DCEF can effectively induce rBMSC migration. A DCEF of 200 mV/mm for 4 h was recommended because of its ability to promote rBMSC migration, proliferation, and osteogenic differentiation. The SDF-1/CXCR4 signaling pathway may play an important role in regulating the DCEF-induced migration of rBMSCs.
关键词: DCEF migration osteogenesis differentiation rBMSCs SDF-1/CXCR-4
A simple umbelliferone based fluorescent probe for the detection of nitroreductase
P. Elmes, Tony D. James
《化学科学与工程前沿(英文)》 2018年 第12卷 第2期 页码 311-314 doi: 10.1007/s11705-017-1697-0
关键词: fragmentation NCOU1 NTR nitroreductase nitrobenzyl-umbelliferone
《工程管理前沿(英文)》 2022年 第9卷 第2期 页码 349-353 doi: 10.1007/s42524-022-0187-3
关键词: Brazil FPSO P67/P70 superlarge dry towing operation construction integration risk control management
标题 作者 时间 类型 操作
Synthesis of zeolite Na-P1 from coal fly ash produced by gasification and its application as adsorbent
Yixin Zhang, Lu Zhou, Liqing Chen, Yang Guo, Fanhui Guo, Jianjun Wu, Baiqian Dai
期刊论文
noncoding RNA LOC646029 functions as a ceRNA to suppress ovarian cancer progression through the miR-627-3p/SPRED1 axis
期刊论文
Clinical characteristics and prognostic values of 1p32.3 deletion detected through fluorescence
Huanping Wang, Haitao Meng, Jinghan Wang, Yinjun Lou, Yile Zhou, Peipei Lin, Fenglin Li, Lin Liu, Huan Xu, Min Yang, Jie Jin
期刊论文
用高光谱发光法研究Cu(Inx,Ga1–x)Se2 (CIGS)模块中由P1引起的功率损耗的成因
César Omar Ramírez Quiroz, Laura-Isabelle Dion-Bertrand, Christoph J. Brabec, Joachim Müller, Kay Orgassa
期刊论文
Adsorption of 1,3-propanediol from synthetic mixture using polymeric resin as adsorbents
TANTAYAKOM, P. PRASITCHOKE, C. MUANGNAPOH
期刊论文
Decitabine induces -mediated immune responses in p53-mutated triple-negative breast cancer: a clinical
期刊论文
Modelling the dynamic response of a solid oxide steam electrolyser to transient inputs during renewable hydrogen production
Qiong CAI, Nigel P. BRANDON, Claire S. ADJIMAN,
期刊论文
Influence of the intensity and loading time of direct current electric field on the directional migration of rat bone marrow mesenchymal stem cells
null
期刊论文
A simple umbelliferone based fluorescent probe for the detection of nitroreductase
P. Elmes, Tony D. James
期刊论文