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Jiao HU,Xiufan LIU
《农业科学与工程前沿(英文)》 2016年 第3卷 第1期 页码 11-24 doi: 10.15302/J-FASE-2016092
关键词: avian influenza virus H9N2 H5N1 novel viruses public health
HEMIPTERAN-TRANSMITTED PLANT VIRUSES: RESEARCH PROGRESS AND CONTROL STRATEGIES
《农业科学与工程前沿(英文)》 2022年 第9卷 第1期 页码 98-109 doi: 10.15302/J-FASE-2021389
About 80% of plant viruses are transmitted by specific insect vectors, especially hemipterans with piercing-sucking mouthparts. Many virus-transmitting insects are also important crop pests that cause considerable losses in crop production. This review summarizes the latest research findings on the interactions between plant viruses and insect vectors and analyzes the key factors affecting insect transmission of plant viruses from the perspectives of insect immunity, insect feeding, and insect symbiotic microorganisms. Additionally, by referring to the latest applications for blocking the transmission of animal viruses, potential control strategies to prevent the transmission of insect-vectored plant viruses using RNAi technology, gene editing technology, and CRISPR/Cas9+ gene-driven technology are discussed.
关键词: control strategies / feeding / immunity / insect vector / microorganism / plant virus
Seroprevalence of influenza viruses in Shandong, Northern China during the COVID-19 pandemic
《医学前沿(英文)》 2022年 第16卷 第6期 页码 984-990 doi: 10.1007/s11684-022-0930-5
关键词: influenza virus seroprevalence antibody COVID-19 cross-sectional study
《环境科学与工程前沿(英文)》 2022年 第16卷 第3期 doi: 10.1007/s11783-021-1469-4
• Distribution of ARGs in decentralized sewage facilities were investigated.
关键词: Decentralized sewage treatment facilities Antibiotic resistance genes Virus Metagenomics Network analysis
null
《医学前沿(英文)》 2017年 第11卷 第4期 页码 471-479 doi: 10.1007/s11684-017-0602-z
Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.
关键词: universal influenza virus vaccine hemagglutinin stalk H7N9
MicroRNAs and hepatitis viruses
Gang LI MD , Xiaojia XIONG MM ,
《医学前沿(英文)》 2009年 第3卷 第3期 页码 265-270 doi: 10.1007/s11684-009-0055-0
null
《医学前沿(英文)》 2017年 第11卷 第4期 页码 449-461 doi: 10.1007/s11684-017-0589-5
In recent years, unexpected outbreaks of infectious diseases caused by emerging and re-emerging viruses have become more frequent, which is possibly due to environmental changes. These outbreaks result in the loss of life and economic hardship. Vaccines and therapeutics should be developed for the prevention and treatment of infectious diseases. In this review, we summarize and discuss the latest progress in the development of small-molecule viral inhibitors against highly pathogenic coronaviruses, including severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus, Ebola virus, and Zika virus. These viruses can interfere with the specific steps of viral life cycle by blocking the binding between virus and host cells, disrupting viral endocytosis, disturbing membrane fusion, and interrupting viral RNA replication and translation, thereby demonstrating potent therapeutic effect against various emerging and re-emerging viruses. We also discuss some general strategies for developing small-molecule viral inhibitors.
关键词: emerging and re-emerging viruses small-molecule inhibitor coronavirus Ebola virus Zika virus life cycle
《医学前沿(英文)》 2023年 第17卷 第5期 页码 1006-1009 doi: 10.1007/s11684-023-1000-3
关键词: family craniofacial microsomia Identification novel mutations
A novel ensemble model for predicting the performance of a novel vertical slot fishway
Aydin SHISHEGARAN, Mohammad SHOKROLLAHI, Ali MIRNOROLLAHI, Arshia SHISHEGARAN, Mohammadreza MOHAMMAD KHANI
《结构与土木工程前沿(英文)》 2020年 第14卷 第6期 页码 1418-1444 doi: 10.1007/s11709-020-0664-x
关键词: novel vertical slot fishway parametric study finite volume method ensemble model gene expression programming
面向公共健康保障的水环境病毒管控路线图 Perspective
刘刚, 曲久辉, Joan Rose, Gertjan Medema
《工程(英文)》 2022年 第12卷 第5期 页码 140-145 doi: 10.1016/j.eng.2020.09.015
水是病毒传播的重要媒介,城市水系统的病毒监控不仅关乎生物安全,而且可以反映病毒在人群中的扩散情况。已有研究表明,无论在发达国家,还是发展中国家,都存在数量大、种类多且组成复杂的介水病原病毒,威胁公众健康。同时,水中病毒相关监测检测工作,已展现出在指示水系统生物安全、水处理工艺表现和社区居民健康等方面的应用潜力。当前,由SARS-CoV-2 引起的新型冠状病毒肺炎疫情,使管控介水病毒与保障公众健康成为全球水环境科技领域的焦点议题。基于对介水病毒研究进展和科技需求的系统分析,本文提出了面向公共健康保障的水环境病毒(COVID-19 等)管控路线图。
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
《医学前沿(英文)》 2023年 第17卷 第2期 页码 330-338 doi: 10.1007/s11684-022-0933-2
关键词: Clouston syndrome whole exome sequencing GJB6 gene novel variant unique phenotype
《机械工程前沿(英文)》 2022年 第17卷 第3期 doi: 10.1007/s11465-022-0691-5
关键词: multifingered hand mechanism design robot safety variable stiffness actuator
2019 novel coronavirus outbreak: a quiz or final exam?
Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao
《医学前沿(英文)》 2020年 第14卷 第2期 页码 225-228 doi: 10.1007/s11684-020-0753-1
A novel stiffness optimization model of space telescopic boom based on locking mechanism
《机械工程前沿(英文)》 2024年 第19卷 第3期 doi: 10.1007/s11465-024-0789-z
关键词: deployable telescopic boom locking mechanism stiffness model clearance error optimization model
标题 作者 时间 类型 操作
Endemicity of H9N2 and H5N1 avian influenza viruses in poultry in China poses a serious threat to poultry
Jiao HU,Xiufan LIU
期刊论文
Distribution of antibiotic resistance genes and their association with bacteria and viruses in decentralized
期刊论文
influenza virus vaccines: what can we learn from the human immune response following exposure to H7 subtype viruses
null
期刊论文
small-molecule viral inhibitors targeting various stages of the life cycle of emerging and re-emerging viruses
null
期刊论文
Identification of novel mutations in and in a family with craniofacial microsomia: evidence of digenic
期刊论文
A novel ensemble model for predicting the performance of a novel vertical slot fishway
Aydin SHISHEGARAN, Mohammad SHOKROLLAHI, Ali MIRNOROLLAHI, Arshia SHISHEGARAN, Mohammadreza MOHAMMAD KHANI
期刊论文
A novel variant in the gene in a large Chinese family with a unique phenotype of Clouston syndrome
期刊论文
Mechanical design, modeling, and identification for a novel antagonistic variable stiffness dexterous
期刊论文
2019 novel coronavirus outbreak: a quiz or final exam?
Jiuyang Xu, Yijun Chen, Hao Chen, Bin Cao
期刊论文