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面向21世纪的中国林业遥感

赵宪文

《中国工程科学》 1999年第1卷第3期页码 16-21

摘要：对21世纪中国林业遥感前景进行了展望。作者认为下一个世纪中国林业遥感发展的主要方向是：包容各种新技术，形成新的技术体系，并与国际接轨；利用遥感的优势，研究森林的宏观状况与作用；与森林经营进一步结合。

关键词：林业遥感持续发展 21世纪

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Fibroblast growth factor 21: a novel metabolic regulator from pharmacology to physiology

null

《医学前沿（英文）》 2013年第7卷第1期页码 25-30 doi: 10.1007/s11684-013-0244-8

摘要：

Fibroblast growth factor 21 (FGF21) is a member of the fibroblast growth factor family. It actually functions as endocrine hormones but does not regulate cell growth and differentiation. It is demonstrated that FGF21 acts on multiple tissue to coordinate carbohydrate and lipid metabolism, including enhancing insulin sensitivity, decreasing triglyceride concentrations, causing weight loss, ameliorating obesity-associated hyperglycemia and hyperlipidemia. Moreover, FGF21 also plays important roles in some physiological processes, such as fasting and feeding, growth hormone axis and thermogenic function of brown adipose tissue. Clinical relevance of FGF21 in humans is still unclear, and the basis and consequences of increased FGF21 in metabolic disease remain to be determined. Both the pharmacological actions and physiological roles make FGF21 attractive drug candidates for treating metabolic disease, but some questions remain to be answered. This article concentrates on recent advances in our understanding of FGF21.

关键词： FGF21 metabolism pharmacology physiology clinical relevance

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21世纪油气工业发展刍议

陈俊武

《中国工程科学》 2000年第2卷第4期页码 21-24

摘要：文章从世界能源消费不断增长的社会发展需求出发，考虑日益苛刻的环境保护政策和举世关心的可持续发展的战略方针，结合今后科学技术的进展，分别从产品需求和资源供应、产品规格和环境保护、非常规石油进入角色及天然气前景引人瞩目四个专题进行论述，对21

关键词： 21世纪石油天然气油气工业

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21世纪人类生活与生存的科技

蒋正华

《中国工程科学》 2002年第4卷第4期页码 1-11

摘要：

从管理学角度回顾了过去百年的世界历史，研究新世纪可能发生的进步，并探讨更好地建立世界和平与合作，实现共同发展的方案。

关键词： 21世纪科技进步人类生活与生存

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Digital manufacturing—the development direction of the manufacturing technology in the 21st century

XIONG You-lun, YIN Zhou-ping

《机械工程前沿（英文）》 2006年第1卷第2期页码 125-130 doi: 10.1007/s11465-006-0021-3

摘要： After introducing the concepts of digital manufacturing technology, the discipline framework of digital manufacturing is presented in the paper by discussing its basic concept, theory foundation, key technology and scientific problems in detail. As the core of the advanced manufacturing technology, digital manufacturing is gradually becoming the main manufacturing technology of the twenty-first century. Firstly, the main features of digital manufacturing are indicated and its key supporting technologies are investigated by grouping them into four levels related to product development, numerical control, production management, and enterprise collaboration, respectively. Moreover, the existing problems in the research on the multi-discipline theory foundation of digital manufacturing such as manufacturing informatics, computational manufacturing, and manufacturing intelligence, are also indicated. Then, the core scientific problems of digital manufacturing are discussed in depth, which focuses on digitization of manufacturing information, modeling of manufacturing constraints, high-speed and high-precision numerical control theory, and Internet-based collaboration and integration. Lastly, the development trends and application perspectives of digital manufacturing are concluded.

关键词： development foundation multi-discipline scientific supporting

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21世纪计算与信息技术的挑战

Wm. A. Wulf

《中国工程科学》 2000年第2卷第10期页码 9-12

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新材料发展现状及21世纪发展趋势研讨会

《中国工程科学》 2001年第3卷第11期页码 88-94

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How diplomacy saved the COP21 Paris Climate Conference, but now, can we save ourselves?

D. Nathaniel MULCAHY, David L. MULCAHY

《能源前沿（英文）》 2018年第12卷第3期页码 344-352 doi: 10.1007/s11708-017-0498-y

摘要：

To solve a problem, three things are necessary: awareness, means, and will. The 2015 COP21 Paris accord was a masterful, perhaps even world-saving, diplomatic advance toward making the world aware of climate change. Some of that success may have been because publications from the IPCC and the National Academy of Science were made available, on line, as prepublication offerings, in order to be widely viewed before the Paris Climate Conference. This provided diplomats and negotiators with the latest information about climate change, its nearness in time, its consequences, and how well current mitigation technologies can succeed. Whatever the reasons, the Paris Climate Conference, was a success. Leaders of 195 nations agreed that climate change is a real and present danger to life as is known to all. This important understanding was accomplished despite the presentation of well established scientific facts which, without very diplomatic handling, could easily have evoked overwhelming political opposition to an agreement and thus another COP failure. In this paper, the fact that how some scientific truths, written specifically to be overlooked, were presented in order to prepare COP21 participants for the conference is explained. Besides, the effectiveness and efficiency of currently favored mitigation policies, the extent of ongoing progress to better ones, and finally, how a new appreciation of climate change consequences can strengthen the will of nation states and industries to work toward solutions are evaluated.

关键词： COP21 Paris climate agreement offsets mitigation IPCC

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新材料发展现状及21世纪发展趋势研讨会论文摘要

《中国工程科学》 2001年第3卷第12期页码 100-101

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Silk Roads for the 21st Century: Engineering Mega-Infrastructure for Development and Sustainability

Tony Marjoram

《工程管理前沿（英文）》 2016年第3卷第3期页码 187-196 doi: 10.15302/J-FEM-2016038

摘要： Infrastructure facilitates the movement of people, the production and distribution of goods and services, and underpins development. Infrastructure is expensive and long-lasting, and needs long-term policy, planning and management, in terms of design, construction, operation and maintenance. Infrastructure relates particularly to engineering and technology. All technological change brings economic, social, cultural and environmental change, planned and unpredicted. Mega levels of technology bring mega levels of change, effects and impacts. Mega infrastructure such as the Silk Road Economic Belt and 21st Century Maritime Silk Road, the “One Belt, One Road” (OBOR) initiative, announced by President Xi Jinping in 2013, will require equally mega policy, planning and management. This paper will discuss policy, planning and management issues relating to mega infrastructure and the OBOR initiative, with particular reference to energy, communications, transportation, health, emergency preparedness and response, and less predictable areas of change, for example in disease prevention and control, within the overall need for economic, environmental and ecological sustainability. The paper will discuss associated needs for education, training and capacity building in engineering. The paper will also refer to lessons learnt from the original Silk Road in the context of the development of civilizations and intercultural dialogue through the transfer of goods, services, technologies, ideas, knowledge, customs, cultures and philosophies, less predictable and unwanted transfers, for example of disease, and the need for awareness, policy, planning and management of such wider issues.

关键词： infrastructure growth development sustainability change new Silk Roads

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新材料发展现状及21世纪发展趋势研讨会论文摘要

null

《中国工程科学》 2002年第4卷第1期页码 91-93

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面向21世纪的超声电机技术

赵淳生

《中国工程科学》 2002年第4卷第2期页码 86-91

摘要：

叙述了新型微特电机——超声电机的特点，回顾了20世纪末期超声电机的发展和应用情况，介绍了南京航空航天大学超声电机研究中心在超声电机研究方面的进展，预测了21世纪国内外市场对超声电机技术的需求

关键词：超声电机压电陶瓷摩擦材料

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Homoharringtonine synergy with oridonin in treatment of t(8; 21) acute myeloid leukemia

Weina Zhang, Ying Lu, Tao Zhen, Xinjie Chen, Ming Zhang, Ping Liu, Xiangqin Weng, Bing Chen, Yueying Wang

《医学前沿（英文）》 2019年第13卷第3期页码 388-397 doi: 10.1007/s11684-018-0624-1

摘要： Collaboration of c-KIT mutations with AML1–ETO (AE) has been demonstrated to induce t(8; 21) acute myeloid leukemia (AML). Targeted therapies designed to eliminate AE and c-KIT oncoproteins may facilitate effective treatment of t(8; 21) AML. Homoharringtonine (HHT) features activity against tumor cells harboring c-KIT mutations, whereas oridonin can induce t(8; 21) AML cell apoptosis and AE cleavage. Therefore, studies should explore the efficacy of combination therapy with oridonin and HHT in t(8; 21) AML. In this study, we investigated the synergistic effects and mechanism of oridonin combined with HHT in t(8; 21) AML cell line and mouse model. The two drugs synergistically inhibited cell viability and induced significant mitochondrial membrane potential loss and apoptosis. Oridonin and HHT induced significant downregulation of c-KIT and its downstream signaling pathways and promoted AE cleavage. HHT increased intracellular oridonin concentration by modulating the expressions of MRP1 and MDR1, thus enhancing the effects of oridonin. The combination of oridonin and HHT prolonged t(8; 21) leukemia mouse survival. In conclusion, oridonin and HHT exert synergistic effects against t(8; 21) leukemia and , thereby indicating that their combination may be an effective therapy for t(8; 21) leukemia.

关键词： AML1–ETO c-KIT homoharringtonine oridonin t(8 21) AML synergistic effect

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21世纪化生武器与防护技术发展趋势

陈翼胜

《中国工程科学》 2000年第2卷第11期页码 25-28

摘要：在世界政治军事形势时有变幻的情况下，21世纪化生武器现实威胁仍然存在，并且由于生物技术等现代科技发展影响，化生武器相关军事技术也将发生重大变化，对于化生武器防护提出了新的要求和挑战。文章讨论了21世纪化生武器及军控基本发展态势，介绍了技术发展趋势，并对未来化生武器防护技术以及医学防护问题的重点需求作了分析和探讨。

关键词：化生武器医学防护化生武器防护技术化生战剂谱

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Sustainable intensification of agriculture is key to feeding Africa in the 21st century

Shenggen FAN

《农业科学与工程前沿（英文）》 2020年第7卷第4期页码 366-370 doi: 10.15302/J-FASE-2020342

摘要：

Africa in facing numerous challenges in the 21st century in feeding its rapidly increasing population. Land resources have become limited due to urbanization and industrialization. The existing agricultural land has been degraded and soil fertility has declined due to unsustainable farming practices. Despite of progress made in the past several decades, hunger and malnutrition in Africa still hinder health, human development and economic growth, which will become even worse in the future if proper measures are not taken. Sustainable intensification is the only solution to tackling both environmental sustainability including climate change and malnutrition, i.e., to produce more foods in terms of nutrients human body needs with less natural resources and carbon emissions. To achieve this vision, innovations in technologies, policies and institutions are essential. The Chinese experience in Agricultural Green Development (AGD) can be shared with Africans when the region is pursuing its sustainable intensification strategy.

关键词： Africa sustainable intensification Agricultural Green Development climate change malnutrition