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Understanding barriers to BIM implementation: Their impact across organizational levels in relation to

Sander SIEBELINK, Hans VOORDIJK, Maaike ENDEDIJK, Arjen ADRIAANSE

《工程管理前沿（英文）》 2021年 第8卷 第2期   页码 236-257 doi: 10.1007/s42524-019-0088-2

摘要： This multiple case study of a contracting firm contributes to understanding the barriers that organizations face during the implementation of building information modeling (BIM) by providing insights into the impact of these barriers across different organizational levels (i.e., from top management to project teams) and by relating these barriers to different degrees of BIM maturity. First, we observe the dominance of barriers related to the motivation, competence, and time capacity of people across all levels of an organization. Second, the cluster of barriers at the middle-management level highlights the important role of this level in reducing these barriers. Third, only those cases with a low level of BIM maturity have struggled with lack of top management support, thereby highlighting the importance of such support in achieving BIM maturity growth. High BIM maturity situations are more prone to externally oriented barriers in attempting to further leverage the benefits of BIM. Our study provides insights on where to focus BIM implementation measures and how to enhance organizational BIM maturity.

关键词： building information modeling     implementation barriers     maturity     organizational levels    

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Avoiding barriers in control of mowing robot

QIU Bai-jing, QIAN Guo-hong, XIANG Zhong-ping, LI Zuo-peng

《机械工程前沿（英文）》 2006年 第1卷 第3期   页码 346-349 doi: 10.1007/s11465-006-0032-0

摘要： Due to complicated barriers, it is difficult to track the path of the mowing robot and to avoid barriers. In order to solve the problem, a method based on distance-measuring sensors and fuzzy control inputs was proposed. Its track

关键词： control     distance-measuring     problem     complicated     difficult    

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IoT sensor-based BIM system for smart safety barriers of hazardous energy in petrochemical construction

《工程管理前沿（英文）》 2022年 第9卷 第1期   页码 1-15 doi: 10.1007/s42524-021-0160-6

摘要： The accidental release of hazardous energy is one of the causes of construction site accidents. This risk is considerably increased during petrochemical plant construction because the project itself is complex in terms of process, equipment, and environment. In addition, a general construction safety barrier hardly isolates and controls site hazardous energy effectively. Thus, this study proposes an Internet of Things (IoT) sensor-based building information modeling (BIM) system, which can be regarded as a new smart barrier design method for hazardous energy in petrochemical construction. In this system, BIM is used to support the identification of on-site hazardous energy, whereas IoT is used to collect the location of on-site personnel in real time. A hazardous energy isolation rule is defined to enable the system to generate a smart barrier on the web terminal window, thereby ensuring the safety of on-site person. This system has been applied to a large-scale construction project in Sinopec for one year and accumulated substantial practical data, which supported the idea about the application of sensor and BIM technology in construction. The related effects of the system on hazardous energy management are also presented in this work.

关键词： IoT     BIM     smart safety barrier     hazardous energy management     petrochemical construction    

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Cleaning the energy sources for water heating among Nanjing households: barriers and opportunities for

Lingyun ZHU,Beibei LIU,Jun BI

《环境科学与工程前沿（英文）》 2014年 第8卷 第5期   页码 757-766 doi: 10.1007/s11783-013-0603-3

摘要： Energy for water heating accounts for an increasing part in residential energy demand in China. An extensive survey was conducted to analyze the determinants of household energy choices for water heaters among residents in Nanjing, China. Two sets of variables were examined as potential influences: building features and household socio-economic characteristics. Results suggest that building features such as gas availability and building structures, and household characteristics such as household head’s education degree and energy-conserving sense are crucial determinants in choosing natural gas as water heater energy. Installation permission for solar water heater, building stories, and residential location serve as determining factors in choosing solar water heaters. Based on these, barriers and opportunities are discussed for transitions toward cleaner water heating energies, and suggestions are given for local governments to promote cleaner energy replacement in China.

关键词： residential energy demand     water heating     multinomial logit model    

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Continuous amino-functionalized University of Oslo 66 membranes as efficacious polysulfide barriers for

《化学科学与工程前沿（英文）》 2023年 第17卷 第2期   页码 194-205 doi: 10.1007/s11705-022-2206-7

摘要： The shuttle effect of soluble polysulfides is a serious problem impeding the development of lithium−sulfur batteries. Herein, continuous amino-functionalized University of Oslo 66 membranes supported on carbon nanotube films are proposed as ion-permselective interlayers that overcome these issues and show outstanding suppression of the polysulfide shuttle effect. The proposed membrane material has appropriately sized pores, and can act as ionic sieves and serve as barriers to polysulfides transport while allowing the passage of lithium ions during electrochemical cycles, thereby validly preventing the shuttling of polysulfides. Moreover, a fast catalytic conversion of polysulfides is also achieved with the as-developed interlayer. Therefore, lithium−sulfur batteries with this interlayer show a desirable initial capacity of 999.21 mAh·g–1 at 1 C and a durable cyclic stability with a decay rate of only 0.04% per cycle over 300 cycles. Moreover, a high area capacity of 4.82 mAh·cm–2 is also obtained even under increased sulfur loading (5.12 mg·cm–2) and a lean-electrolyte condition (E/S = 4.8 μL·mg–1).

关键词： lithium−sulfur batteries     amino-functionalized University of Oslo 66 membrane     polysulfide     interlayer    

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Drivers and barriers to engage enterprises in environmental management initiatives in Suzhou Industrial

Bing ZHANG, Jun BI, Beibei LIU

《环境科学与工程前沿（英文）》 2009年 第3卷 第2期   页码 210-220 doi: 10.1007/s11783-009-0014-7

摘要： Small- and medium-sized enterprises (SMEs) play an important role in sustainable development not only for their significant contribution to China’s economy, but also for their big share of total discharged pollutants. Therefore, this research takes the enterprises in Suzhou Industrial Park, China as the case study to investigate the environmental management practices of SMEs, and identify drivers and barriers to engaging businesses in environmental management initiatives. It is shown that, as in other countries, SMEs are less active in adopting environmental management initiatives than larger companies. Legislation remains the key driver to engage SMEs in environmental management initiatives. Based on the analysis, policy recommendations are also presented.

关键词： small- and medium-sized enterprises (SMEs)     environmental management initiative     Suzhou industrial park    

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Barriers and countermeasures in developing traditional Chinese medicine in Europe

null

《医学前沿（英文）》 2016年 第10卷 第3期   页码 360-376 doi: 10.1007/s11684-016-0455-x

摘要：

Traditional Chinese medicine (TCM) is one of the unique cultural treasures of Chinese; it represents a significant feature and prominent advantage of the healthcare cause in China. Data in this paper were from World Health Organization, Chinese Bureau of Statistics, China National Knowledge Infrastructure, and PubMed. In recent years, TCM has established a solid foundation in Europe, which made great strides in legislation, education, research, and international exchange, and has enjoyed a vast development space in the continent. Now, TCM is embracing unprecedented development opportunities in Europe. At the same time, the stiff international competition poses a grave threat to China’s TCM industry. With multiple cultural, legal, and institutional challenges, as well as talent shortages in the way, TCM is now facing many difficulties in Europe. To fully prepare and enact active and vigorous steps to seize opportunities, we should have a clear picture about the serious challenges hampering TCM development in Europe. The TCM development at overseas markets has shifted from a spontaneous trade activity into a national strategy spearheaded by the government and participated in by multiple stakeholders. We should make a systematic, comprehensive, and sustainable push in fields such as TCM therapy, healthcare, education, research, culture, and industry development. The ultimate goal is to bring TCMs to the global market and allow them to play a role in safeguarding public health along with modern medicines.

关键词： traditional Chinese medicine     Europe     development    

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IMPROVING NITROGEN SAFETY IN CHINA: NITROGEN FLOWS, POLLUTION AND CONTROL

《农业科学与工程前沿（英文）》 2022年 第9卷 第3期   页码 465-474 doi: 10.15302/J-FASE-2022454

摘要：

● It is necessary to address the N flows and their impacts on environment in China for sustainable N management.

关键词： barriers     future management     ammonia emissions     nitrogen input     water N pollution    

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Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

《化学科学与工程前沿（英文）》 2013年 第7卷 第1期   页码 9-19 doi: 10.1007/s11705-013-1306-9

摘要： Oral insulin delivery has received the most attention in insulin formulations due to its high patient compliance and, more importantly, to its potential to mimic the physiologic insulin secretion seen in non-diabetic individuals. However, oral insulin delivery has two major limitations: the enzymatic barrier that leads to rapid insulin degradation, and the mucosal barrier that limits insulin’s bioavailability. Several approaches have been actively pursued to circumvent the enzyme barrier, with some of them receiving promising results. Yet, thus far there has been no major success in overcoming the mucosal barrier, which is the main cause in undercutting insulin’s oral bioavailability. In this review of our group’s research, an innovative silica-based, mucoadhesive oral insulin formulation with encapsulated-insulin/cell penetrating peptide (CPP) to overcome both enzyme and mucosal barriers is discussed, and the preliminary and convincing results to confirm the plausibility of this oral insulin delivery system are reviewed. In vitro studies demonstrated that the CPP-insulin conjugates could facilitate cellular uptake of insulin while keeping insulin’s biologic functions intact. It was also confirmed that low molecular weight protamine (LMWP) behaves like a CPP peptide, with a cell translocation potency equivalent to that of the widely studied TAT. The mucoadhesive properties of the produced silica-chitosan composites could be controlled by varying both the pH and composition; the composite consisting of chitosan (25 wt-%) and silica (75 wt-%) exhibited the greatest mucoadhesion at gastric pH. Furthermore, drug release from the composite network could also be regulated by altering the chitosan content. Overall, the universal applicability of those technologies could lead to development of a generic platform for oral delivery of many other bioactive compounds, especially for peptide or protein drugs which inevitably encounter the poor bioavailability issues.

关键词： insulin     cell penetrating peptide     mucoadhesive composites     oral delivery    

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Barriers to advancing nanotechnology to better improve and translate nanomedicines

Yuwei WANG,David W. Grainger

《化学科学与工程前沿（英文）》 2014年 第8卷 第3期   页码 265-275 doi: 10.1007/s11705-014-1442-x

摘要： Engineered nanomaterials and nanotechnologies promise many benefits to enhance both and performance. This is now manifest in the increasing number of reported biomedical products under development and testing that contain nanotechnologies as their distinguishing performance—enhancing components. In many cases, nano-sized materials are selected to provide a specific functional aspect that contributes to improved medical performance, either or . Nanoparticles are most commonly exploited in diverse roles in topical lotions and creams, solubilization aids, for and diagnostic and targeting agents in nanomedicines and theranostics. Despite fundamental scientific excitement and many claims to nanotechnology-based improvements in new biomedical applications, several fundamental and long-standing challenges remain to be addressed using nanomedicines to make clinically important progress. This review addresses several issues that must be fairly and objectively reported and then overcome to provide truly credible performance for nanomedicines.

关键词： nanotechnology     nanomedicine     drug delivery     therapeutic     target delivery    

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Controlled drug delivery systems: the next 30 years

Yeonhee YUN,Byung Kook LEE,Kinam PARK

《化学科学与工程前沿（英文）》 2014年 第8卷 第3期   页码 276-279 doi: 10.1007/s11705-014-1426-x

摘要： The drug delivery scientists need to reexamine the advances made during the past 60 years, analyze our current abilities, and design the future technologies that will propel us to achieve the next level of drug delivery technologies. History shows that the first generation (1G) of drug delivery research during 1950–1980 was quite productive, while the second generation (2G) technologies developed during 1980–2010 were not as prolific. The ultimate goal of drug delivery research is to develop clinically useful formulations to treat various diseases. Effective drug delivery systems can be developed by overcoming formulation barriers and/or biological barriers. The engineering approach has a limit in solving the problem, if biological difficulties are not clearly identified and understood. The third generation (3G) drug delivery systems will have to focus on understanding the biological barriers so that they can be overcome by engineering manipulation of the drug delivery systems. Advances in the next 30 years will be most accelerated by starting open dialogues without any preconceived ideas on drug delivery technologies. The new generation of drug delivery scientists needs to be aware of the successes and limitations of the existing technologies to design the new technologies for meaningful advances in the future.

关键词： drug delivery     history     formulation barriers     nanotechnology     clinical product    

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China’s Sponge City construction: A discussion on technical approaches

Haifeng Jia, Zheng Wang, Xiaoyue Zhen, Mike Clar, Shaw L. Yu

《环境科学与工程前沿（英文）》 2017年 第11卷 第4期 doi: 10.1007/s11783-017-0984-9

摘要： Since 2014, China has been implementing the Sponge City Construction initiative, which represents an enormous and unprecedented effort by any government in the world for achieving urban sustainability. According to preliminary estimates, the total investment on the Sponge City Plan is roughly 100 to 150 million Yuan (RMB) ($15 to $22.5 million) average per square kilometer or 10 Trillion Yuan (RMB) ($1.5 Trillion) for the 657 cities nationwide. The Sponge City Plan (SCP) calls for the use of natural processes such as soil and vegetation as part of the urban runoff control strategy, which is similar to that of low impact development (LID) and green infrastructure (GI) practices being promoted in many parts of the world. The SCP includes as its goals not only effective urban flood control, but also rainwater harvest, water quality improvement and ecological restoration. So far, the SCP implementation has encountered some barriers and challenges due to many factors. The present paper presents a review of those barriers and challenges, offers discussions and recommendations on several technical aspects such as control goals and objectives; planning/design and construction of LID/GI practices; performance evaluation. Several key recommendations are proposed on Sponge City implementation strategy, Site-specific regulatory framework and technical guidance, Product innovation and certification, LID/GI Project financing, LID/GI professional training and certification, public outreach and education. It is expected that the successful implementation of the SCP not only will bring about a sustainable, eco-friendly urbanization process in China, but also contribute enormously to the LID/GI research and development with the vast amount of relevant data and experiences generated from the Sponge City construction projects.

关键词： Low impact development (LID)     Green infrastructure (GI)     Sponge City     Barriers     Construction strategies    

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可再生电能制氢路线的科研前沿、技术瓶颈和解决方案展望 Review

胡国平, 陈超, 卢合顺, 吴越, 刘聪敏, 陶乐夫, 门昱含, 何广利, 李刚

《工程（英文）》 2020年 第6卷 第12期   页码 1364-1380 doi: 10.1016/j.eng.2020.04.016

摘要：

由于电转氢（power to hydrogen, P2H）技术工艺成熟，灵活性高，目前其工程验证项目较多，有效的技术数据和经济数据来源广泛，因此电转氢可以有效地解决可再生能源供给与市场需求之间的不平衡问题。利用现行的天然气管网对氢气运输并在运输终端生产高纯度的氢气产品是一种可行的方案。本文通过全面地分析电制氢的研究现状，指出现行技术难点和寻找技术突破点并提供有效的解决方案，同时也提出未来电转氢方向基础研究和工业示范的发展契机。现有研究结果表明，在天然气管道中添加10%左右的氢气对于天然气管道安全、寿命和用户设备的影响较小，甚至可以忽略不计，从而适当地延长已有的天然气管道的资产价值。在产业链下游通过膜、吸附或其他有效的技术来对富氢天然气（HENG）进行分离是获得高纯氢气的有效方法，其关键在于对高选择性的分离技术和高氢容量的新材料的研发。另外，文中指出膜-吸附耦合工艺从HENG中制高纯氢，电化学分离氢（氢泵）的规模化、可行性和能耗分析研究是重要的发展方向，而低温冷冻分离技术在液化天然气（LNG）为主要产品时才具有一定的可行性。本文还讨论了其他相关技术和操作难点以及发展机遇，如水源的重要性、副产物（氧气）的利用和技术本身对于环境的影响等。本文对于促进读者对电转氢技术的理解和氢能经济的发展具有重要的指导意义。

关键词： 电转氢     可再生能源     氢能     能源    

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标题 作者 时间 类型 操作

Understanding barriers to BIM implementation: Their impact across organizational levels in relation to

Sander SIEBELINK, Hans VOORDIJK, Maaike ENDEDIJK, Arjen ADRIAANSE

期刊论文

Avoiding barriers in control of mowing robot

QIU Bai-jing, QIAN Guo-hong, XIANG Zhong-ping, LI Zuo-peng

期刊论文

IoT sensor-based BIM system for smart safety barriers of hazardous energy in petrochemical construction

期刊论文

Cleaning the energy sources for water heating among Nanjing households: barriers and opportunities for

Lingyun ZHU,Beibei LIU,Jun BI

期刊论文

Continuous amino-functionalized University of Oslo 66 membranes as efficacious polysulfide barriers for

期刊论文

Drivers and barriers to engage enterprises in environmental management initiatives in Suzhou Industrial

Bing ZHANG, Jun BI, Beibei LIU

期刊论文

Barriers and countermeasures in developing traditional Chinese medicine in Europe

null

期刊论文

IMPROVING NITROGEN SAFETY IN CHINA: NITROGEN FLOWS, POLLUTION AND CONTROL

期刊论文

Overcoming oral insulin delivery barriers: application of cell penetrating peptide and silica-based nanoporous

Huining HE, Junxiao YE, Jianyong SHENG, Jianxin WANG, Yongzhuo HUANG, Guanyi CHEN, Jingkang WANG, Victor C YANG

期刊论文

Barriers to advancing nanotechnology to better improve and translate nanomedicines

Yuwei WANG,David W. Grainger

期刊论文

Controlled drug delivery systems: the next 30 years

Yeonhee YUN,Byung Kook LEE,Kinam PARK

期刊论文

China’s Sponge City construction: A discussion on technical approaches

Haifeng Jia, Zheng Wang, Xiaoyue Zhen, Mike Clar, Shaw L. Yu

期刊论文

可再生电能制氢路线的科研前沿、技术瓶颈和解决方案展望

胡国平, 陈超, 卢合顺, 吴越, 刘聪敏, 陶乐夫, 门昱含, 何广利, 李刚

期刊论文